Liver transplant: When is it necessary?

Liver transplant: When is it necessary?
The liver, a vital organ that plays a fundamental role in the detoxification and metabolism functions of the human body, can sometimes present serious challenges in its functioning.

When liver diseases reach a point of being life-threatening, a liver transplant becomes a hope of salvation for that patient. In this article, we will explain when it is necessary to perform a liver transplant, the reasons behind this intervention, its implications and risks. If you want to know more about this topic, continue reading!

When is it necessary to perform a liver transplant?

Is necessary when the original organ is so damaged that it cannot fulfill its vital functions. Severe liver diseases, such as cirrhosis, chronic hepatitis, liver cancer, and inherited metabolic diseases, can lead to this critical situation. Determining the need for a transplant is based on a number of factors, such as: the patient’s general health, the degree of liver damage, and the response to previous medical treatments.

It is important to visit your doctor if you think you might have liver disease.

Reasons why a liver transplant is performed

1.- Advanced cirrhosis: generally caused by chronic alcoholism or chronic hepatitis infection, which gradually damages the liver tissue until reaching an advanced stage where the liver cannot function properly, considerably deteriorating the patient’s quality of life.

2.- Liver cancer: in the case of advanced stage, a transplant may be the only curative option. However, not all patients with liver cancer are candidates for a transplant, as they must meet other sets of conditions.

3.- Hereditary metabolic diseases: such as Wilson’s disease or glycogen storage disease, they can lead to a serious deterioration in the functionality of the liver. In these cases, a liver transplant may be necessary to improve quality of life and prolong survival.

What does the surgery involve?

Liver transplant is a high-level surgery in which the damaged liver is replaced with a healthy one from a compatible donor (it can be a portion of healthy liver). Before surgery, the patient is thoroughly evaluated to determine its suitability. Next, a donor is sought, which may be a living donor or a deceased donor, depending on the situation.

After surgery, the patient will require intensive care and close monitoring to prevent rejection of the transplanted organ and apply the treatment indicated by the treating physician and manage any complications.

A surgery requires the participation of various medical specialists.

What are your risks?

While liver transplant can save lives, it is not without risks. The main ones are:

  • Organ rejection: the patient’s immune system may recognize the new liver as an invader and try to destroy it. This is controlled with immunosuppressive medications, but can still be a challenge to overcome.

  • Infections: after surgery, patients are more susceptible to infections due to suppression or vulnerability of the immune system.

  • Surgical complications: as with any surgery, there are inherent risks associated with the operation itself, such as bleeding or problems with wound healing.

In conclusion, liver transplant is a vital option for those patients whose lives are threatened by serious liver diseases. Careful assessment, selection of appropriate donors, and risk management are critical to the success of this intervention. Despite the challenges, liver transplantation offers a second chance and hope for a healthier life for those who desperately need it.

Daniela Malavé Montilla, writing
Bachelor in Social Communication

Eugenia Jiménez Alvaréz, editor
Assistant to the coordination of Fundahígado América
Bachelor in Biomedical Sciences

Share on facebook
Share on twitter
Share on google
Share on linkedin


Liver and overall health

Explore the vital role of the liver in digestion, detoxification, immune function and overall health, understanding its functions and implications for maintaining a healthy lifestyle.

Hepatic Complications

Explore the liver’s functions and learn to identify and manage complications. Discover modern treatments to preserve liver health and your overall well-being.

World Transplant Day: A Gift That Transforms Lives

A healthy organ from a living donor can transform the life of someone in need. World Transplant Day reminds us of the importance of living-donor organ donation, especially for liver transplantation, which offers a second chance to people with severe liver diseases.



Génesis is 3 years old and was born in Costa Rica with a congenital liver disease.


Elías is a young adolescent with an advanced liver disease.


Jin received a segment of his father´s liver in May 2015.